The parents of Alfie Evans, who has been at the centre of a life-support treatment dispute, have lost the latest round of a legal battle.

Three Court of Appeal judges have dismissed another challenge by Tom Evans and Kate James, who are both in their early twenties and from Liverpool.

The couple, who want Alfie to be cared for in a Rome hospital, appealed following a ruling made by a High Court judge late on Tuesday.

But appeal judges on Wednesday dismissed their challenge following a hearing in London which the couple did not attend.